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Product Name
Human Lipopolysaccharide binding protein/LBP (His Tag)
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Description
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
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Protein name
Lipopolysaccharide-binding protein
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Protein short names
BPIFD2; LY88; LBP; RP23-407H16.4; LIPOPOLYSACCHARIDE BINDING PROTEIN; MGC22233
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Uniprot ID
Q8TCF0
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Gene Name
LBP
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human LBP (NP_004130.2) extracellular domain (Met 1-Val 481) was fused with the a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human LBP consists of 467 amino acids and has a predicted molecular mass of 52.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhLBP is approximately 62 kDa due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human LBP / Lipopolysaccharide binding Protein (His Tag) SDS-PAGE
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