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Product Name
LILRB3 Polyclonal Antibody
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Description
Polyclonal antibody to LILRB3
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Tested applications
WB
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Species reactivity
Human
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Alternative names
LILRB3 antibody; CD85A antibody; HL9 antibody; ILT-5 antibody; ILT5 antibody; LILRA6 antibody; LIR-3 antibody; LIR3 antibody; PIR-B antibody; PIRB antibody; leukocyte immunoglobulin like receptor B3 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human LILRB3 (NP_001307889.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - LILRB3 Polyclonal Antibody
Western blot analysis of extracts of Jurkat cells, using LILRB3 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 60s.
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Background
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"