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Mouse Latexin (His Tag) recombinant protein

Cat.#: 501770

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Special Price 532.2 USD

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Product Information

  • Product Name
    Mouse Latexin (His Tag) recombinant protein
  • Documents
  • Description
    Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4 (By similarity). May play a role in inflammation.
  • Protein name
    Latexin
  • Protein short names
    MGC144352; LXN; LATEXIN; TCI; ECI; MGC144353
  • Uniprot ID
    Q14BZ3
  • Gene Name
    Lxn
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse LXN (NP_058033.2) (Glu 2-Glu 222) was expressed, with a polyhistide tag at the N-terminus.
  • Protein Species
    Mouse
  • Molecular weight
    The recombinant mouse LXN consisting of 228 amino acids and has a calculated molecular mass of 26.3 kDa. The apparent molecular mass of the rmLXN is approximately 32 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to inhibit carboxypeptidase-A1 cleavage of the colorimetric peptide substrate Ac-Phe-Thiaphe-OH in the presence of 5,5'Dithiobis(2-nitrobenzoic acid) (DTNB) (Edwards, K.M. et al, 1999, J. Biol. Chem. 274:30468). The IC50 value is <2.0 nM .
  • Validations

    Mouse LXN / Latexin Protein (His Tag) SDS-PAGE

    Mouse LXN / Latexin Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"