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Product Name
Human MFG-E8 / lactadherin / MFGE8 (His Tag) recombinant protein
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Description
Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
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Protein name
Lactadherin
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Protein short names
MFGM; SPERM SURFACE PROTEIN SP47; SPERM SURFACE PROTEIN HP47; SED1; HST19888; EDIL1; EGF/FACTOR VIII; SPAG10; AA408458; HP47; BREAST EPITHELIAL ANTIGEN BA46; O-ACETYL DISIALOGANGLIOSIDE SYNTHASE; MP47; BA46; P47; SPERM ASSOCIATED ANTIGEN 10; LACTADHERIN; MILK FAT GLOBULE GLYCOPROTEIN; MFG-E8; HMFG; OACGD3S; MEDIN; AI325141
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Uniprot ID
Q08431
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Gene Name
MFGE8
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human MFGE8 isoform 1 (Q08431-1) (Met 1-Cys 387) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human MFGE8 comprises 374 amino acids and has a predicted molecular mass of 42 kDa. The apparent molecular mass of rh MFGE8 is approximately 45 kDa in SDS-PAGE under reducing conditions.
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Purity
> 88 % as determined by SDS-PAGE
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Validations
Human MFG-E8 / lactadherin / MFGE8 Protein (His Tag) SDS-PAGE
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