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Product Name
Human DCXR / HCR2 (His Tag) recombinant protein
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Description
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
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Protein name
L-xylulose reductase
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Protein short names
L-XYLULOSE REDUCTASE; SPERM SURFACE PROTEIN P34H; RP23-84C12.19-003; KIDCR; DICARBONYL/L-XYLULOSE REDUCTASE; 1810027P18RIK; CARBONYL REDUCTASE II; PNTSU; SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY 20C; MEMBER 1; HCRII; DCR; P34H; XR; DCXR; CARBONYL REDUCTASE 2; KIDNEY DICARBONYL REDUCTASE; DIACETYL/L-XYLULOSE REDUCTASE; SDR20C1; 0610038K04RIK; DICARBONYL L-XYLULOSE REDUCTASE; HCR2
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Uniprot ID
Q7Z4W1
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Gene Name
DCXR; SDR20C1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human DCXR (Q7Z4W1) (Met1-Cys244) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human DCXR consists of 259 amino acids and predicts a molecular mass of 27.8 KDa. It migrates as an approximately 29 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human DCXR / HCR2 Protein (His Tag) SDS-PAGE
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