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Product Name
Recombinant Human KRAS (C118S) Protein
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Description
This product is a soluble recombinant human KRAS4b (C118S mutant) protein (amino acid 1-169) with an N-terminal 6×His tag. The protein is produced via Escherichia coli high-efficiency expression and purification, with outstanding solubility and high purity. The C118S point mutation is constructed on the basis of native KRAS4b 1-169aa sequence, suitable for KRAS post-translational modification research, protein stability analysis and tumor pathogenesis study.
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Protein name
GTPase KRas
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Uniprot ID
P01116
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Gene Name
C-K-RAS; C-K-RAS; c-Ki-ras; c-Ki-ras2; CFC2; K-Ras; K-Ras 2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KI-RAS; KRAS1; KRAS2; NS; NS3; OES; RALD; RALD2; RASK2
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
DNA encoding 1‑169 aa (P01116‑2, C118S) was fused with a 6‑His tag.
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Sequence
MNHKVHHHHH HENLYFQSMT EYKLVVVGAG GVGKSALTIQ LIQNHFVDEY DPTIEDSYRK QVVIDGETCL LDILDTAGQE EYSAMRDQYM RTGEGFLCVF AINNTKSFED IHHYREQIKR VKDSEDVPMV LVGNKSDLPS RTVDTKQAQD LARSYGIPFI ETSAKTRQGV DDAFYTLVRE IRKHKEK
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 21.53 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 23.7 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant Human KRAS (C118S) Protein SDS-PAGE
M: Marker; Lane 1: KRAS (C118S); Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"