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Product Name
KLF7 antibody
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Description
KLF7 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells. Positive IP detected in K-562 cells. Observed molecular weight by Western-blot: 33 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
KLF7 antibody; Krueppel like factor 7 antibody; UKLF antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of KLF7 recombinant protein (Accession Number: XM_017005164). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:1000
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:112084(KLF7 antibody) at dilution of 1:300
IP Result of anti-KLF7 (IP:Catalog No:112084, 4ug; Detection:Catalog No:112084 1:300) with K-562 cells lysate 3200ug.
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Background
KLF7, also named as UKLF, is a 302 amino acid protein, which contains three C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family. KLF7 is ubiquitous and highly expressed in brain and spinal cord in the adult, and in kidney and brain in the embryo. KLF7 as a transcriptional activator localizes in the nucleus and binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence.
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References
- Gao Y, Liu XF, Lu XC, Ma C, Cao J, Fan L. Protective effects of atorvastatin against oxidized LDL-induced downregulation of KLF expression in EA.hy926 cells. International journal of molecular medicine. 30(2):330-6. 2012.
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