• Klebsiella neo/kan/nptII recombinant protein

Klebsiella neo/kan/nptII recombinant protein

Cat.#: 518100

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Product Information

  • Product Name
    Klebsiella neo/kan/nptII recombinant protein
  • Documents
  • Description
    Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
  • Protein name
    Aminoglycoside 3'-phosphotransferase
  • Protein short names
    kan; nptII
  • Uniprot ID
    P00552
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Klebsiella neo/kan/nptII Met1-Phe264 is expressed.
  • Protein Species
    Klebsiella
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Klebsiella neo/kan/nptII recombinant protein

    Klebsiella neo/kan/nptII recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"