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Product Name
Human KLHL2 (GST Tag) recombinant protein
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Description
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
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Protein name
Kelch-like protein 2
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Protein short names
KLHL2; 6030411N21RIK; KELCH-LIKE 2; KELCH-LIKE PROTEIN 2; AU020744; ACTIN-BINDING PROTEIN MAYVEN; ABP-KELCH; MKIAA4249; MAYVEN (DROSOPHILA); KELCH; MAV; MAYVEN
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Uniprot ID
O95198
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Gene Name
KLHL2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human KLHL2 (AAH36468.1) (Met1-Pro306) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human KLHL2 /GST chimera consists of 540 amino acids and has a predicted molecular mass of 62.2 kDa. It migrates as an approximately 63 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human KLHL2 Protein (GST Tag) SDS-PAGE
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