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Product Name
Mouse IL-6R/CD126 (His Tag) recombinant protein
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Description
Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
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Protein name
Interleukin-6 receptor subunit alpha
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Protein short names
MGC104991; IL6R; IL-6R; CD126; IL-6R-ALPHA; IL-6R-1; IL6RA
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Uniprot ID
Q3URV7
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Gene Name
Il6ra; Il6r
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse IL6R? (NP_034689.2) extracellular domain (Ile 44-Glu 357) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse IL6R? comprises 349 amino acids with a predicted molecular mass of 39 kDa. As a result of glycosylation, it migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Mouse IL6RA / CD126 Protein (His Tag) SDS-PAGE
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