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Product Name
Sus scrofa (Pig) IL-6 (pig) recombinant protein
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Description
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
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Protein name
Interleukin 6
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Protein short names
HGF; BSF2; IFNB2; IL-6; IL6; HSF
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Uniprot ID
P26893
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Gene Name
IL-6; IL6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the sus scrofa IL6 (NP_999564.1) (Pro29-Met212) was expressed with an initial Met.
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Protein Species
Sus scrofa (Pig)
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Molecular weight
The recombinant sus scrofa IL6 consists 185 amino acids and predicts a molecular mass of 21.2 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Sus scrofa (pig) IL6 / IL-6 Protein
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"