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Product Name
Mouse IL-4R/CD124 (His Tag) recombinant protein
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Description
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
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Protein name
Interleukin-4 receptor subunit alpha
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Protein short names
IL4RA; MGC118473; CD124; IL4R
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Uniprot ID
Q3U905
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Gene Name
Il4r; Il4ra
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Il4r (NP_001008700.1) (Met1-Arg233) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Il4r consists 219 amino acids and predicts a molecular mass of 25.8 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Il4r protein SDS-PAGE
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