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Human IL-25 (Fc Tag) recombinant protein

Cat.#: 501585

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Product Information

  • Product Name
    Human IL-25 (Fc Tag) recombinant protein
  • Documents
  • Description
    Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
  • Protein name
    Interleukin-25
  • Protein short names
    UNQ3120; PRO10272; IL-17E; IL17E; RATTUS NORVEGICUS; RGD1561632
  • Uniprot ID
    Q9H293
  • Gene Name
    IL25; IL17E; UNQ3120/PRO10272
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human IL25 (Tyr 33-Gly177) (NP_073626.1) was fused with the Fc region of human IgG1 at the N-terminus via a polypeptide linker.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL25/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 403 amino acids and predicts a molecular mass of 45 KDa. As a result of glycosylation, the apparent molecular mass of rh IL25/Fc monomer is approximately 50-60 KDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized human IL17BR-His (Cat:503945) at 10 μg/ml (100 μl/well) can bind human Fc-IL25 (Cat:501585), The EC50 of human Fc-IL25 (Cat:501585) is 1.7-4.2 μg/ml.
  • Validations

    Human IL25 Protein (Fc Tag) SDS-PAGE

    Human IL25 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"