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Human IL17BR / IL17RB / IL-17 Receptor B (Fc Tag) recombinant protein

Cat.#: 501590

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Product Information

  • Product Name
    Human IL17BR / IL17RB / IL-17 Receptor B (Fc Tag) recombinant protein
  • Documents
  • Description
    Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
  • Protein name
    Interleukin-17 receptor B
  • Protein short names
    IL-17BR; IL17BR; CRL4; UNQ2501/PRO19612; EVI27; IL-17RH1; IL-17RB; IL17RH1; IL-17ER; MGC5245; IL17RB
  • Uniprot ID
    Q9NRM6
  • Gene Name
    IL17RB; CRL4; EVI27; IL17BR; UNQ2501/PRO19612
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IL17BR (NP_061195.2) (Met1-Gly289) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL17BR/Fc is a disulfide-linked homodimer. The reduced monomer comprises 513 amino acids and has a predicted molecular mass of 56.9 kDa. The apparent molecular mass of the protein is approximately 67 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human IL17BR-Fc at 10μg/mL (100μL/well) can bind biotinylated human Fc-IL25 (Cat:501585).
    The EC50 of human Fc-IL25 (Cat:501585) is 4.5-10.4ng/mL.
  • Validations

    Human IL17BR / IL17RB / IL-17 Receptor B Protein (Fc Tag) SDS-PAGE

    Human IL17BR / IL17RB / IL-17 Receptor B Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"