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Product Name
Human IL1F10 / IL-38 (His Tag) recombinant protein
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Description
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
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Protein name
Interleukin-1 family member 10
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Protein short names
IL1-THETA; IL1HY2; IL-1HY2; RP23-176J12.7; FIL1-THETA; IL-38; FKSG75; UNQ6119/PRO20041
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Uniprot ID
Q8WWZ1
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Gene Name
IL1F10; FIL1T; IL1HY2; IL38; FKSG75; UNQ6119/PRO20041
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Source/Expression Host
Yeast
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Expression Plasmid/cDNA
A DNA sequence encoding the human IL1F10 (AAK68048.1) (Met1-Trp152) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human IL1F10 consists 162 amino acids and predicts a molecular mass of 18.4 kDa.
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Purity
> 90 % as determined by SDS-PAGE.
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Validations
Human IL1F10 / IL-38 Protein (His Tag)
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"