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  • Influenza NP (147-155) peptide

Influenza NP (147-155) peptide

Not For Human Use, Lab Use Only.

Cat.#: 301476

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Influenza NP (147-155) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    TYQRTRALV
  • Sequence
    Thr-Tyr-Gln-Arg-Thr-Arg-Ala-Leu-Val
  • Length (aa)
    9
  • Peptide Purity (HPLC)
    99.82%
  • Molecular Formula
    C48H82N16O14
  • Molecular Weight
    1107.29
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The Influenza NP (147-155) peptide is a nonamer epitope derived from the nucleoprotein (NP) of influenza A virus. This peptide is specifically recognized by cytotoxic T lymphocytes (CTLs) in the context of the major histocompatibility complex class I molecule Kd. It represents a conserved region within the NP, which is an internal viral protein, making it a target for cross-reactive cellular immune responses against different influenza strains.

    In experimental studies, this peptide has been utilized to investigate antigen presentation and CTL induction. When expressed within bacterial vectors, such as Listeria monocytogenes, the NP (147-155) epitope can be delivered to the host cell cytoplasm, enabling its processing and presentation via the MHC class I pathway. This leads to the activation of NP-specific CD8+ T cells, which are capable of lysing influenza-infected cells. The epitope's role is primarily studied in the context of understanding fundamental mechanisms of antiviral cellular immunity.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Ikonomidis G, Portnoy DA, Gerhard W, Paterson Y. Influenza-specific immunity induced by recombinant Listeria monocytogenes vaccines. Vaccine. 1997 Mar;15(4):433-40. doi: 10.1016/s0264-410x(96)00188-0. PMID: 9141215.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"