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  • Influenza HA (529-537) peptide

Influenza HA (529-537) peptide

Not For Human Use, Lab Use Only.

Cat.#: 301570

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* Buy 1 get 1 free (?) What is TFA?

Special Price 140.80 USD

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Product Information

  • Product Name
    Influenza HA (529-537) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    IYATVAGSL
  • Sequence
    Ile-Tyr-Ala-Thr-Val-Ala-Gly-Ser-Leu
  • Length (aa)
    9
  • Peptide Purity (HPLC)
    95.5%
  • Molecular Formula
    C41H67N9O13
  • Molecular Weight
    894.04
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The Influenza HA (529-537) peptide, with the amino acid sequence IYATVAGSL, is derived from the hemagglutinin protein of the Influenza A/Japan/305/57 (H2N2) virus. This nine-amino-acid region is located within the transmembrane domain of hemagglutinin and serves as an epitope recognized by H-2Kd-restricted cytotoxic T-lymphocyte clones. Structural analysis indicates that specific residues within the peptide are critical for immune recognition. For instance, the glycine at position 7 is essential for binding by H2-subtype-specific CTL clones, while conserved threonine at position 4 and alanine at position 6 contribute to cross-reactive recognition by CTL clones that target both H1 and H2 subtypes. The peptide shares compatibility with a corresponding region in the H1 subtype hemagglutinin, highlighting a conserved structural motif that enables targeted immune responses across influenza subtypes.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Tamura M, Kuwano K, Kurane I, Ennis FA. Definition of amino acid residues on the epitope responsible for recognition by influenza A virus H1-specific, H2-specific, and H1- and H2-cross-reactive murine cytotoxic T-lymphocyte clones. J Virol. 1998 Nov;72(11):9404-6. doi: 10.1128/JVI.72.11.9404-9406.1998. PMID: 9765498; PMCID: PMC110370.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"