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Product Name
Recombinant IGLC3 protein (His tag)
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Description
Recombinant Immunoglobulin lambda constant 3 (IGLC3) fragment (amino acids 1-106) from Homo sapiens. This high-purity protein includes the complete Ig-like domain, providing a reliable tool for investigating antibody structure, antigen binding, and B-cell mediated immune responses in research applications.
Immunoglobulin lambda constant 3 (IGLC3) represents the constant region of immunoglobulin light chains, which are critical components of antibodies produced by B lymphocytes. These immunoglobulins function as either membrane-bound receptors on B cells or as secreted glycoproteins. In the recognition phase of humoral immunity, membrane-bound immunoglobulins bind specific antigens, triggering B-cell expansion and differentiation into antibody-secreting plasma cells. Secreted immunoglobulins then execute the effector phase, leading to antigen elimination. Each immunoglobulin's antigen binding site is formed by variable domains from one heavy chain and its associated light chain, enabling high-affinity
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Protein name
Immunoglobulin lambda constant 3
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Uniprot ID
P0DOY3
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Gene Name
IGLC3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-106 aa (P0DOY3) were fused with C-terminal 6His tag.
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Sequence
MSKIKGQPKA APSVTLFPPS SEELQANKAT LVCLISDFYP GAVTVAWKAD SSPVKAGVET TTPSKQSNNK YAASSYLSLT PEQWKSHKSY SCQVTHEGST VEKTVAPTEC SLEHHHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 12.90 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 15 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant IGLC3 protein (His tag) SDS-PAGE
M: Marker; Lane 1: IGLC3; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"