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Product Name
Ibalizumab reference antibody
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Description
Anti-CD4 Antibody (Ibalizumab)
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Tested applications
ELISA
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Species reactivity
Human CD4
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Isotype
IgG4SP
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Preparation
Recombinant expression and purified from CHO cells.
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Clonality
Monoclonal
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Formulation
0.1 M Pro-Ac, 20 mM Arg, pH 5.0
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Storage instructions
-80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
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Validations
SDS-PAGE
Anti-CD4 Antibody (ibalizumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
SEC-HPLC
The purity of Anti-CD4 Antibody (ibalizumab) is more than 95%, determined by SEC-HPLC.
Bioactivity: FACS
Human CD4 CHO cells were stained with Anti-CD4 Antibody (ibalizumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.16 ug/mL.
Function: Pseudoviral Inhibition
Anti-CD4 Antibody (ibalizumab) Pseudoviral inhibition was evaluated using Tzmbl.The IC50 was approximately 0.441 nM.
Function: Activation Inhibition
Anti-CD4 Antibody (ibalizumab) Activation inhibition was evaluated using PBMC. The max induction fold was approximately 1.71
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"