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  • Hym-355 peptide

Hym-355 peptide

Not For Human Use, Lab Use Only.

Cat.#: 318146

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Product Information

  • Product Name
    Hym-355 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    FPQSFLPRG-NH2
  • Sequence
    H-Phe-Pro-Gln-Ser-Phe-Leu-Pro-Arg-Gly-NH2
  • Length (aa)
    9
  • Peptide Purity (HPLC)
    96.87%
  • Molecular Formula
    C50H73N13O12
  • Molecular Weight
    1047.2
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Hym-355 is a neuropeptide originally isolated from the freshwater hydrozoan Hydra magnipapillata. Its amino acid sequence is FPQSFLPRG-NH2, featuring a characteristic C-terminal amidation. Research has demonstrated that Hym-355 can trigger oocyte maturation and subsequent spawning in the marine hydrozoan jellyfish Cytaeis uchidae, although its stimulatory effect is weaker compared to other peptides like Hym-53. The biological activity is dependent on the amidated C-terminus, as the non-amidated form, Hym-355-OH, is ineffective.

    Immunohistological analyses have shown that neurons positive for the C-terminal PRG-NH2 sequence of Hym-355 are present in the ovarian ectodermal epithelium of Cytaeis uchidae. The peptide does not act directly on isolated oocytes, indicating its target is likely somatic cells within the ovarian tissue. These findings suggest Hym-355 functions as a signaling molecule, potentially involved in neuropeptide-mediated pathways regulating reproductive events in cnidarians.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Takeda N, Nakajima Y, Koizumi O, Fujisawa T, Takahashi T, Matsumoto M, Deguchi R Neuropeptides trigger oocyte maturation and subsequent spawning in the hydrozoan jellyfish Cytaeis uchidae Mol Reprod Dev 2013 Mar;80(3):223-32
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"