• HYD1 peptide

HYD1 peptide

Not For Human Use, Lab Use Only.

Cat.#: 319391

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Product Information

  • Product Name
    HYD1 peptide
  • Documents
  • Sequence Shortening
    H-kikmviswkG-NH2, all D-AA
  • Sequence
    H-Lys-Ile-Lys-Met-Val-Ile-Ser-Trp-Lys-Gly-NH2, all D-AA
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    97.27%
  • Molecular Formula
    C56H97N15O11S
  • Molecular Weight
    1188.54
  • Source
    Synthetic
  • Form
    Powder
  • Description

    HYD1 is a synthetic D-amino acid peptide with the sequence kikmviswkg. This linear 10-mer peptide exhibits distinct bioactive properties depending on its presentation. When immobilized, the core sequence kmvixw serves as the minimal element required to support cell adhesion. In solution, HYD1 demonstrates potent bioactivity in blocking cell migration, with the essential motif xkmviswxx identified as critical for this function. Additionally, the peptide activates ERK signaling through the sequence ikmviswxx, with the shortest common active sequence across all assays being iswkg. The peptide's interaction with integrin subunits α6 and α3 suggests its role in modulating cell-matrix interactions.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Sroka TC, Marik J, Pennington ME, Lam KS, Cress AE. The minimum element of a synthetic peptide required to block prostate tumor cell migration. Cancer Biol Ther. 2006 Nov;5(11):1556-62. doi: 10.4161/cbt.5.11.3461. Epub 2006 Nov 30. PMID: 17102593; PMCID: PMC2704570.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"