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Product Name
Human ZNRF1/NIN283 (His tag) recombinant protein
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Description
E3 ubiquitin-protein ligase ZNRF1 contains one ring-type zinc finger, high expressed in the nervous system and developing brain, low expressed in testis and thymus. ZNRF1 mediates the ubiquitination of AKT1 and GLUL, so it plays a role in neuron cells differentiation. It also has a role in the establishment and maintenance of neuronal transmission and plasticity. ZNRF1 regulates Schwann cells differentiation by mediating ubiquitination of GLUL.
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Protein name
zinc and ring finger 1(ZNRF1)
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Protein short names
NIN283
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Uniprot ID
Q8ND25
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ZNRF1/NIN283 Pro74-Thr178 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ZNRF1/NIN283 (His tag) recombinant protein
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