-
Product Name
Human ZNF658 Recombinant protein (His tag)
- Documents
-
Description
Mediates transcriptional repression in response to zinc. Represses several genes, including SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'-C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region. May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, as well as those of several ribosomal proteins, thus coordinating this highly zinc-demanding process with the available zinc supply. {PubMed:25582195}.
-
Protein name
Zinc finger protein 658
-
Uniprot ID
Q5TYW1
-
Gene Name
ZNF658
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human ZNF658 (NP_001304845.1) 73-247 aa was fused with the polyhistidine tag
-
Protein Species
Human
-
Activity
Not tested.
-
Validations
Recombinant human ZNF658 SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"