Human YTHDF1 Recombinant protein (GST tag)

Human YTHDF1 Recombinant protein (GST tag)

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Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440). {PubMed:24284625, PubMed:26046440, PubMed:26318451}.

YTH domain-containing family protein 1

C20orf21

Q9BYJ9

YTHDF1; C20orf21

E. coli

A DNA sequence encoding the human YTHDF1 (NP_060268.2) 210-559 aa was fused with the N-terminal GST tag

Human

Not tested.