Human UPB1/BUP1 (His tag) recombinant protein

Cat.#: 519210

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Product Information

  • Product Name
    Human UPB1/BUP1 (His tag) recombinant protein
  • Documents
  • Description
    β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta aminoisobutyric acid, respectively. Defects in β-Ureidopropionase are the cause of β-Ureidopropionase deficiency that is characterized by muscular hypotonia, dystonic movements, scoliosis, microcephaly and severe developmental delay.
  • Protein name
    beta-ureidopropionase 1(UPB1)
  • Protein short names
    BUP1
  • Uniprot ID
    Q9UBR1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human UPB1/BUP1 Met1-Glu384 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human UPB1/BUP1 (His tag) recombinant protein

    Human UPB1/BUP1 (His tag) recombinant protein

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