Human UBP1 Recombinant protein (GST tag)

Human UBP1 Recombinant protein (GST tag)

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Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. {, PubMed:10644752, PubMed:2006421, PubMed:8114710}.

Upstream-binding protein 1

LBP1

Q9NZI7

UBP1; LBP1

E. coli

A DNA sequence encoding the human UBP1 (XP_047304802.1) 283-543 aa was fused with the N-terminal GST tag

Human

Not tested.