Human TREML1/TLT1/UNQ1825/PRO3438 (Fc tag) recombinant protein

Cat.#: 519199

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Product Information

  • Product Name
    Human TREML1/TLT1/UNQ1825/PRO3438 (Fc tag) recombinant protein
  • Documents
  • Description
    Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
  • Protein name
    triggering receptor expressed on myeloid cells like 1(TREML1)
  • Protein short names
    TLT1; UNQ1825; PRO3438
  • Uniprot ID
    Q86YW5
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TREML1/TLT1/UNQ1825/PRO3438 Gln16-Pro162 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TREML1/TLT1/UNQ1825/PRO3438 (Fc tag) recombinant protein

    Human TREML1/TLT1/UNQ1825/PRO3438 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"