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Product Name
Human TRDN Recombinant protein (GST tag)
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Description
Contributes to the regulation of lumenal Ca2+ release via the sarcoplasmic reticulum calcium release channels RYR1 and RYR2, a key step in triggering skeletal and heart muscle contraction. Required for normal organization of the triad junction, where T-tubules and the sarcoplasmic reticulum terminal cisternae are in close contact (By similarity). Required for normal skeletal muscle strength. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. {UniProtKB:E9Q9K5, PubMed:22422768}.
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Protein name
Triadin
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Uniprot ID
Q13061
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Gene Name
TRDN
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TRDN (NP_001242949.1) 75-293 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TRDN SDS-PAGE
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