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Product Name
Human TRAT1/TCRIM/HSPC062 (His tag) recombinant protein
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Description
T-Cell Receptor-Associated Transmembrane Adapter 1 (TRAT1) is a single-pass type III membrane protein. TRAT1 exists as a disulfide-linked homodimer and is strongly expressed in the thymus, and to a lesser extent in the spleen, lymph node, and peripheral blood lymphocytes. TRAT1 is phosphorylated on tyrosines by LCK or FYN upon TCR activation. Its function is to stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
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Protein name
T cell receptor associated transmembrane adaptor 1(TRAT1)
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Protein short names
TCRIM; HSPC062
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Uniprot ID
Q6PIZ9
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TRAT1/TCRIM/HSPC062 Asn29-Asn186 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TRAT1/TCRIM/HSPC062 (His tag) recombinant protein
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