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Product Name
Human TRAF1 Recombinant protein (His tag)
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Description
Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. {PubMed:10692572, PubMed:16323247, PubMed:18429822, PubMed:19287455, PubMed:19698991, PubMed:20385093}.
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Protein name
TNF receptor-associated factor 1
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Protein short names
EBI6
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Uniprot ID
Q13077
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Gene Name
TRAF1; EBI6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TRAF1 (NP_001177874.1) 173-295 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TRAF1 SDS-PAGE
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