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Product Name
Human TPSB2/TPS2 (His tag) recombinant protein
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Description
Tryptases are Trypsin-like Serine Proteases. β-Tryptases are the main isoenzymes in mast cells. Βtryptases form active tetramers with heparin proteoglycan. In the tetramer, the unique arrangement of the active sites facing a narrow central pore, β-Tryptases are resistant to macromolecule protease inhibitors . When mast cells are activated, β-Tryptases are released and participate in provoking inflammatory conditions . β-Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic disorders.
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Protein name
tryptase beta 2 (gene/pseudogene)(TPSB2)
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Protein short names
TPS2
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Uniprot ID
P20231
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TPSB2/TPS2 Ala19-Pro275 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TPSB2/TPS2 (His tag) recombinant protein
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