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  • Human TOLLIP (His tag) recombinant protein

Human TOLLIP (His tag) recombinant protein

Cat.#: 519649

Special Price 156.8 USD

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Product Information

  • Product Name
    Human TOLLIP (His tag) recombinant protein
  • Documents
  • Description
    Toll-Interacting Protein (TOLLIP) is a member of the tollip family. TOLLIP localizes to the cytoplasm. It contains one C2 domain and one CUE domain. TOLLIP is an inhibitory adaptor protein for Toll-like receptors (TLR). The Toll-like receptors pathway is a part of the immune system that recognize structurally conserved molecular patterns of microbial pathogens, resulting in an inflammatory immune response. TOLLIP constitutes a complex with Tom1 to regulate endosomal transferring of ubiquitinated proteins. TOLLIP can negative regulate Toll-like receptors signaling, which may limit the production of proinflammatory mediators during the process of inflammation and infection.
  • Protein name
    toll interacting protein(TOLLIP)
  • Uniprot ID
    Q9H0E2
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TOLLIP Ala2-Pro274 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TOLLIP (His tag) recombinant protein

    Human TOLLIP (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"