Human THY1 recombinant protein (C-cleavage)

Human THY1 recombinant protein (C-cleavage)

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.

Thy-1 cell surface antigen, isoform CRA_a

CD90

B0YJA4

Thy-1 cell surface antigen, isoform CRA_a; Thy-1 membrane glycoprotein variant 2; cDNA FLJ33325 fis, clone BNGH42008832, highly similar to THY-1 MEMBRANE GLYCOPROTEIN; cDNA FLJ33677 fis, clone BRAWH2002125, highly similar to THY-1 MEMBRANE GLYCOPROTEIN

Human Cells

A DNA sequence encoding the human THY1 (NP_006279.2) (Met1-Cys130) was expressed with five amino acids (DDDDK) at the C-terminus.

Human

The recombinant human THY1 consists of 117 amino acids and predicts a molecular mass of 13.2 kDa.

> 95 % as determined by SDS-PAGE.