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Human TBC1D17 Recombinant protein (His tag)

Cat.#: 513388

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human TBC1D17 Recombinant protein (His tag)
  • Documents
  • Description
    Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known. {PubMed:22854040, PubMed:24752605}.
  • Protein name
    TBC1 domain family member 17
  • Uniprot ID
    Q9HA65
  • Gene Name
    TBC1D17
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human TBC1D17 (NP_078958.2) 1-350 aa was fused with the polyhistidine tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human TBC1D17 SDS-PAGE

    Recombinant human TBC1D17 SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"