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Product Name
Human SPESP1/UNQ732/PRO1418 (His tag) recombinant protein
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Description
Sperm Equatorial Segment Protein 1 (SPESP1) is a member of the SPESP1 family. SPESP1 is highly expressed in the testis, where it is localized to the acrosome of postmeiotic stages of spermiogenesis; it is expressed at lower levels in the placenta and fetal lung. SPESP1 is involved in the multicellular organisimal development. Disruption of SPESP1 leads to abnormal distribution of sperm proteins resulting in a detached membrane from the equatorial segment and less fertile sperm. SPESP1 may interact with IZUMO1 and MN9 antigen and it contains an N-glycosylation site as well as several cAMP-dependent kinase, protein kinase C, and casein kinase II consensus phosphorylation sites.
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Protein name
sperm equatorial segment protein 1(SPESP1)
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Protein short names
UNQ732; PRO1418
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Uniprot ID
Q6UW49
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SPESP1/UNQ732/PRO1418 Tyr20-Tyr350 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SPESP1/UNQ732/PRO1418 (His tag) recombinant protein
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