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Product Name
Human SOD2 (His tag) recombinant protein
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Description
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron disease, and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.
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Protein name
superoxide dismutase 2, mitochondrial(SOD2)
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Uniprot ID
P04179
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SOD2 Lys25-Lys222 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SOD2 (His tag) recombinant protein
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