Human SENP7/KIAA1707/SSP2/SUSP2 (His tag) recombinant protein

Cat.#: 518009

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Product Information

  • Product Name
    Human SENP7/KIAA1707/SSP2/SUSP2 (His tag) recombinant protein
  • Documents
  • Description
    Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
  • Protein name
    SUMO1/sentrin specific peptidase 7(SENP7)
  • Protein short names
    KIAA1707; SSP2; SUSP2
  • Uniprot ID
    Q9BQF6
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human SENP7/KIAA1707/SSP2/SUSP2 Met695-Ala864 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human SENP7/KIAA1707/SSP2/SUSP2 (His tag) recombinant protein

    Human SENP7/KIAA1707/SSP2/SUSP2 (His tag) recombinant protein

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