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Product Name
Human SENP7/KIAA1707/SSP2/SUSP2 (His tag) recombinant protein
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Description
Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
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Protein name
SUMO1/sentrin specific peptidase 7(SENP7)
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Protein short names
KIAA1707; SSP2; SUSP2
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Uniprot ID
Q9BQF6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SENP7/KIAA1707/SSP2/SUSP2 Met695-Ala864 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SENP7/KIAA1707/SSP2/SUSP2 (His tag) recombinant protein
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