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Product Name
Human SCO1/SCOD1 (GST tag) recombinant protein
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Description
Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by high rates of Oxidative Phosphorylation (OxPhos). SCO1 is thought to play a important role in cellular copper homeostasis, mitochondrial redox signaling and insertion of copper into the active site of COX. The defects of SCO1 can result in Mitochondrial Complex IV Deficiency (MT-C4D). A disorder of the mitochondrial respiratory chain has heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs.
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Protein name
SCO1, cytochrome c oxidase assembly protein(SCO1)
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Protein short names
SCOD1
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Uniprot ID
O75880
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SCO1/SCOD1 Gly132-Ser300 is expressed with a GST tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SCO1/SCOD1 (GST tag) recombinant protein
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