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Product Name
Human RTCD1 Recombinant protein (His tag)
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Description
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
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Protein name
RNA 3'-terminal phosphate cyclase
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Protein short names
RPC; RPC1; RTC1; RTCD1
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Uniprot ID
O00442
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Gene Name
RTCA; RPC; RPC1; RTC1; RTCD1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human RTCA (NP_001124313.1) 1-379 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human RTCD1(Full length) SDS-PAGE
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