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Product Name
Human PTP4A2/PRL2/PTPCAAX2/BM-008 (His tag) recombinant protein
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Description
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
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Protein name
protein tyrosine phosphatase type IVA, member 2(PTP4A2)
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Protein short names
PRL2; PTPCAAX2; BM-008
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Uniprot ID
Q12974
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PTP4A2/PRL2/PTPCAAX2/BM-008 Met1-Gln167 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PTP4A2/PRL2/PTPCAAX2/BM-008 (His tag) recombinant protein
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