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Product Name
Human PSMD10 recombinant protein
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Description
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
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Protein name
proteasome 26S subunit, non-ATPase 10(PSMD10)
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Uniprot ID
O75832
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PSMD10 Met1-Gly226 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PSMD10 recombinant protein
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