• Human PRTN3/MBN (His tag) recombinant protein

Human PRTN3/MBN (His tag) recombinant protein

Cat.#: 518034

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Product Information

  • Product Name
    Human PRTN3/MBN (His tag) recombinant protein
  • Documents
  • Description
    Proteinase-3 is a neutral serine proteinase that belongs to the peptidase S1 family and Elastase subfamily. It contains one peptidase S1 domain and it is expressed mainly in neutrophil granulocytes. The primary function of Proteinase-3 is thought to be degradation of extracellular proteins at sites of inflammation, but excessive or prolonged proteolytic activity may cause harmful effects in the body. It is the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
  • Protein name
    proteinase 3(PRTN3)
  • Protein short names
    MBN
  • Uniprot ID
    P24158
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PRTN3/MBN Ala26-Arg249 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PRTN3/MBN (His tag) recombinant protein

    Human PRTN3/MBN (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"