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  • Human PRKG1/PRKG1B/PRKGR1A/PRKGR1B (His tag) recombinant protein

Human PRKG1/PRKG1B/PRKGR1A/PRKGR1B (His tag) recombinant protein

Cat.#: 519287

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Product Information

  • Product Name
    Human PRKG1/PRKG1B/PRKGR1A/PRKGR1B (His tag) recombinant protein
  • Documents
  • Description
    cGMP-Dependent Protein Kinase 1 (PRKG1) belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family. PRKG1 contains one AGC-kinase C-terminal domain, two cyclic nucleotide-binding domains, and one protein kinase domain. PRKG1 is mainly expressed in the lung and placenta. PRKG1 acts as a key mediator of the nitric oxide (NO)/cGMP signaling pathway. PRKG1 can phosphorylate many proteins that regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-signaling pathway, and other processes involved in several aspects of the CNS like axon guidance, hippocampal and cerebellar learning, circadian rhythm, and nociception.
  • Protein name
    protein kinase, cGMP-dependent, type I(PRKG1)
  • Protein short names
    PRKG1B; PRKGR1A; PRKGR1B
  • Uniprot ID
    Q13976-2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PRKG1/PRKG1B/PRKGR1A/PRKGR1B Gly2-Pro686 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PRKG1/PRKG1B/PRKGR1A/PRKGR1B (His tag) recombinant protein

    Human PRKG1/PRKG1B/PRKGR1A/PRKGR1B (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"