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Product Name
Human PRG3/MBPH/UNQ486/PRO1002 (His tag) recombinant protein
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Description
Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.
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Protein name
proteoglycan 3, pro eosinophil major basic protein 2(PRG3)
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Protein short names
MBPH; UNQ486; PRO1002
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Uniprot ID
Q9Y2Y8
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PRG3/MBPH/UNQ486/PRO1002 Leu18-Phe225 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PRG3/MBPH/UNQ486/PRO1002 (His tag) recombinant protein
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