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Product Name
Human PPP1R1A/IPP1 (His tag) recombinant protein
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Description
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
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Protein name
protein phosphatase 1 regulatory inhibitor subunit 1A(PPP1R1A)
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Protein short names
IPP1
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Uniprot ID
Q13522
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PPP1R1A/IPP1 Met1-Val171 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PPP1R1A/IPP1 (His tag) recombinant protein
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