Human PPIC/CYPC (Trx & His tag) recombinant protein

Cat.#: 518187

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Product Information

  • Product Name
    Human PPIC/CYPC (Trx & His tag) recombinant protein
  • Documents
  • Description
    Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains.
  • Protein name
    peptidylprolyl isomerase C(PPIC)
  • Protein short names
    CYPC
  • Uniprot ID
    P45877
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PPIC/CYPC Lys31-Asp182 is expressed with a Trx, 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PPIC/CYPC (Trx & His tag) recombinant protein

    Human PPIC/CYPC (Trx & His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"