Human PLXDC1/TEM3/TEM7 (His tag) recombinant protein

Human PLXDC1/TEM3/TEM7 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs).

plexin domain containing 1(PLXDC1)

TEM3; TEM7

Q8IUK5

Human Cells

A DNA sequence encoding the Human PLXDC1/TEM3/TEM7 Leu19-Thr426 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.