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Product Name
Human PFKFB1/F6PK/PFRX (His tag) recombinant protein
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Description
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
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Protein name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1(PFKFB1)
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Protein short names
F6PK; PFRX
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Uniprot ID
P16118
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PFKFB1/F6PK/PFRX Ser2-Tyr471 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PFKFB1/F6PK/PFRX (His tag) recombinant protein
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