Human PDGFB/PDGF2/SIS recombinant protein

Cat.#: 518328

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Product Information

  • Product Name
    Human PDGFB/PDGF2/SIS recombinant protein
  • Documents
  • Description
    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
  • Protein name
    platelet derived growth factor subunit B(PDGFB)
  • Protein short names
    PDGF2; SIS
  • Uniprot ID
    P01127
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PDGFB/PDGF2/SIS Ser82-Thr190 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PDGFB/PDGF2/SIS recombinant protein

    Human PDGFB/PDGF2/SIS recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"