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Product Name
Human PADI4/PAD4/PADI5/PDI5 (His tag) recombinant protein
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Description
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
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Protein name
peptidyl arginine deiminase 4(PADI4)
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Protein short names
PAD4; PADI5; PDI5
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Uniprot ID
Q9UM07
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PADI4/PAD4/PADI5/PDI5 Met1-Pro663 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PADI4/PAD4/PADI5/PDI5 (His tag) recombinant protein
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